London (UK), May 2nd-4th 2012
Introduction to compartmental neuronal modelling with neuroConstruct and recent advances in rapid 2-photon imaging
Meeting venue: University College of London. Link here
This course, being run by the Silver Lab @ UCL, will provide an introduction to 3D biophysically detailed neuronal modelling and recent advances in 2-photon imaging methods for studying rapid neuronal signalling. Creation of multicompartmental, conductance based neuronal models has been greatly facilitated by software packages such as NEURON andGENESIS and a range of detailed cell and network models are available which are faithful to the anatomical and biophysical properties of the corresponding biological entities.neuroConstruct is an application which facilitates the construction and analysis of such models through a 3D graphical interface and automates code generation for a number of widely used simulators.
The course will give an overview of the field of detailed compartmental modelling and how it can complement experimental approaches including 2-photon imaging. It will consist of some introductory lectures on modeling and imaging, provide hands on experience of using neuroConstruct, introduce the existing cortical, cerebellar and hippocampal models which are already available in this format, and outline the process of creating new models from experimental data. The course will also cover the simulator independent model description language NeuroML and the growing number of tools available for handling models in this format.